Intro to SEDNTERP, a handy tool for AUC data interpretation

John Philo · Monday, 24 August 2026, 14:15 – 16:15 · Session 3
Room 101260

Introduction to SEDNTERP(suitable for novice AUC users) and its use for calculating:

  • solvent density, viscosity, and refractive index
  • sample partial specific volume, hydration, and specific refractive increment (dn/dc)
  • standardized sedimentation or diffusion coefficients (s20,w or D20,w¬) from raw experimental values
  • sedimentation or diffusion coefficients extrapolated to zero concentration, and their concentration-dependence coefficients ksand kD
  • hydrodynamic parameters from SV or diffusion results:
  • anhydrous sphere radius, and corresponding maximum possible sedimentation and diffusion coefficients
  • sample frictional coefficient, f/f0 ratio, and Stokes radius
  • sample overall hydrodynamic shape and hydration characteristics (max hydration, Perrin P function, actual molecular size and shape for ellipsoid or cylinder models)